Cambridge-Africa

Researchers' Database

Researchers from across the University of Cambridge and its affiliated institutes are engaging with the initiatives of the Cambridge-Africa Programme by carrying out collaborative research with African colleagues, and/or supporting African fellows.

annettee 019

 

Photograph:

Dr Annettee Nakimuli, Makerere University and MUII PhD Fellow, and her Cambridge co-supervisor Professor Ashley Moffett, Department of Pathology.

 

 

 

In order to encourage new collaborations with African researchers and to support African PhD students and post-doctoral fellows, we have built (and are continuously expanding) a database of current and potential Cambridge collaborators and their expertise. The Cambridge researchers listed are either already engaging with, or have indicated their interest in being matched to Africans who have similar research interests. Cambridge researchers who would like to get involved do not need to have a pre-prepared project available, or existing African links, in order to be included in the database. If you would like your details to be included, please complete the (short and painless) registration form.

Note to African researchers searching for a Cambridge collaborator: Please be aware that any enquiries about potential collaboration with a Cambridge researcher should to be directed to one of the Cambridge-Africa team or enquiries@cambridge-africa.cam.ac.uk in the first instance. They will then put you in touch with the Cambridge researcher if there is an appropriate match in the research interests. Thanks for your cooperation.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Dr Daniel Fazakerley (Studying insulin action or resistance in cultured cells) More Info

Position & Affiliation:
Principal Investigator, Institute of Metabolic Science
www.mrl.ims.cam.ac.uk/research/our-research-teams/…

Research Interests:

We study how insulin stimulates glucose transport into fat and muscle cells, and how this process breaks down in disease. Impaired insulin-stimulated glucose transport in muscle and fat is a major contributor to whole body insulin resistance and progression ot type 2 diabetes. We aim to find out more about how insulin signalling regulates GLUT4 trafficking and how this is altered in insulin resistance.

Publications:
Williamson A, Norris DM … Mohlke KL, Wheeler E, O’Rahilly S, Fazakerley DJ, Langenberg C. Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake. Nat Genet. 2023 55(6):973-983.

Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance. Fazakerley DJ, van Gerwen J, Cooke KC, Duan X, Needham EJ, Díaz-Vegas A, Madsen S, Norris DM, Shun-Shion AS, Krycer JR, Burchfield JG, Yang P, Wade MR, Brozinick JT, James DE, Humphrey SJ.Nat Commun. 2023 Feb 18;14(1):923. doi: 10.1038/s41467-023-36549-2.

A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology. Diaz-Vegas A, Norris DM, Jall-Rogg S, Cooke KC, Conway OJ, Shun-Shion AS, Duan X, Potter M, van Gerwen J, Baird HJ, Humphrey SJ, James DE, Fazakerley DJ, Burchfield JG.Life Sci Alliance. 2022 Oct 25;6(1):e202201585. doi: 10.26508/lsa.202201585.

Dr Brian Ferguson (Innate immune responses to virus infection) More Info

Position & Affiliation:
University Lecturer in Innate Immunity, Pathology Department
www.fergusonlab.path.cam.ac.uk

Research Interests:

We study the innate immune response to virus infection in a wide variety of models with the aim of understanding host and viral factors that influence both the outcome of infection and the development of optimal memory immunity.

Publications:

Julia Zinngrebe, Eva Rieser, Lucia Taraborrelli, Nieves Peltzer, Torsten Hartwig,Hongwei Ren, View ORCID ProfileIldikó Kovács,Cornelia Endres, Peter Draber, Maurice Darding, Silvia von Karstedt, Johannes Lemke, Balazs Dome,Michael Bergmann, Brian J. Ferguson, Henning Walczak
LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation
https://doi.org/10.1084/jem.20160041

Hongwei Ren, Brian J. Ferguson, Carlos Maluquer de Motes, Rebecca P. Sumner, Laura E. R Harman, Geoffrey L. Smith
Enhancement of CD8+ T-cell memory by removal of a vaccinia virus nuclear factor-κB inhibitor. Immunology 2015.10.1111/imm.12422

Brian J Ferguson Daniel S Mansur Nicholas E Peters Hongwei Ren Geoffrey L Smith DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASE, 2012

http://dx.doi.org/10.7554/eLife.00047

Prof Rob Foley (Human Evolution And Adaptation In Africa) More Info

Position & Affiliation:
Leverhulme Professor of Human Evolution and Fellow of King’s College
www.human-evol.cam.ac.uk

Research Interests:

Human evolution and adaptation in Africa.

Current African links: Kenya, with the Turkana Basin Institute, the National Museums of Kenya, and The British Institute in Eastern Africa.

Prof Robin Franklin (Stem Cells & Regenerative Medicine) More Info

Position & Affiliation:
Professor of Neuroscience, Dept of Veterinary Medicine and MRC Centre for Stem Cell Biology and Regenerative Medicine, Brain Repair Centre

Research Interests:

Stem cells and regenerative medicine. Biology of stem cell-mediated regenerative processes in CNS and especially oligodendrocyte regeneration. http://www.neuroscience.cam.ac.uk/directory/profile.php?rjf1000 and http://www.vet.cam.ac.uk/research/investigators/franklin.html and http://www.stemcells.cam.ac.uk/

Publications:
(1) Fancy SP et al. (2009), Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes & Development 23:1571-85.

(2) Franklin RJM and ffrench-Constant C (2008),

(3) Shen S et al. (2008), Age-dependent epigenetic control of differentiation inhibitors: a critical determinant of remyelination efficiency. Nature Neuroscience 11: 1024-1034.