Cambridge-Africa

Researchers' Database

Researchers from across the University of Cambridge and its affiliated institutes are engaging with the initiatives of the Cambridge-Africa Programme by carrying out collaborative research with African colleagues, and/or mentoring African fellows.

annettee 019

Photograph:

Dr Annettee Nakimuli, Makerere University and MUII PhD Fellow, and her Cambridge co-supervisor Professor Ashley Moffett, Department of Pathology.

 

 

 

In order to recruit excellent post-doctoral researchers and doctoral students from Africa into Cambridge for training, we have built (and are continuously expanding) a database of current and potential Cambridge collaborators/mentors and their expertise. The >180 Cambridge researchers listed are either already engaging with, or have indicated their interest in being matched to Africans who have similar research interests. Cambridge researchers who would like to get involved do not need to have a pre-prepared project available, or existing African links, in order to be included in the database. If you would like your details to be included, please complete the (short and painless) registration form.

Note to African researchers searching for a Cambridge mentor/collaborator: Please be aware that any enquiries about potential mentorship by, or collaboration with a Cambridge researcher need to be directed to one of the Cambridge-Africa Programme staff in the first instance. They will then put you in touch with the Cambridge researcher if there is an appropriate match in the research interests. Thanks for your cooperation.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Dr John P. Carr (Plant Pathogens and Disease, particularly Viruses) More Info

Position & Affiliation:
Senior Lecturer, Plant Sciences Department
http://www.plantsci.cam.ac.uk/directory/carr-john

Research Interests:

I am interested in the induction of disease by plant pathogens and how disease agents, particularly viruses, alter interactions of plant hosts with other organisms. Work ranges from detailed molecular genetic approaches, through analysis of natural products through to organism-organism interactions.

Suggestions for specific projects/topics: I can supervise or mentor students or scientific visitors on topics in plant virology (including development of resistance), plant pathology or aphid-plant interactions.

Existing African or developing country associations: I co-ordinate a £2M programme between Cambridge University, Rothamsted Research, Biosciences East and Central Africa (BecA) and CIAT (Uganda) to translate basic research on insect-plant interactions to aid in protection of beans, which are a major source of protein to resource-poor farmers in East Africa. The programme is funded by the SCPRID programme.  http://www.bbsrc.ac.uk/web/FILES/Publications/1210-scprid.pdf - see “Leaving a bad taste in aphids’ mouths” ).

Publications:
1. Westwood, J.H., Lewsey, M.G., Murphy, A.M., Tungadi, T., Bates, A., Gilligan, C.A. and Carr, J.P. (2014) Interference with jasmonic acid- regulated gene expression is a general property of viral suppressors of RNA silencing but only partly explains virus-induced changes in plant-aphid interactions. Journal of General Virology  95: 733–739. 


2. Westwood, JH, Groen, SC, Du, Z, Tungadi, T, Lewsey, MG, Luang-In, V, Murphy, AM, Rossiter, J, Powell, G, Smith, AG, Carr, JP (2013). A trio of viral proteins tunes aphid-plant interactions in Arabidopsis thaliana.  PLoS ONE 8(12): e83066.

3. Ziebell, H., Murphy, A.M., Groen, S.C., Tungadi, T., Westwood, J.H., Lewsey, M.G., Moulin, M., Kleczkowski, A., Smith, A.G., Stevens, M., Powell, G., and Carr, J.P. (2011). 'Cucumber mosaic virus and its 2b RNA silencing suppressor modify plant-aphid interactions in tobacco.' Scientific Reports 1: 187.

Professor Mark Carrington ( Trypanosome / Host Interactions ) More Info

Position & Affiliation:
Reader, Dept of Biochemistry
http://web.me.com/mc115/mclab/home.html

Research Interests:

Interaction between trypanosomes and their mammalian hosts.

Possible project topics: (1) Geographic variation in VSG repertoire. (2) Development of serodiagnostics for T. brucei, T. congolense and T. vivax.

Current African links: Previously supervised Kenyan PhD students.

Publications:
(1) Jones N et al. (2007). J. Biol. Chem. 283, 3584-3593. Structure of a type I VSG C-terminal domain and GPI-anchor.

(2) Thomson R et al. (2009). Proc. Natl. Acad. Sci. 106, 19509-19514. Gene therapy with baboon trypanosome lytic factor eliminates both animal and human infective African trypanosomes.

(3) Kramer S et al. (2008). J Cell Sci. 121, 3002-3014. Heat shock causes a decrease in polysomes and appearence of stress granules in trypanosomes independently of eIF2a phosphorylation at a position equivalent to serine 51.

Dr Goylette Chami (Social networks and the control of neglected tropical diseases; Disease/Symptom/Diagnosis co-morbidity networks; Behavioral experiments to elicit preferences for treatment-seeking health behaviors) More Info

Position & Affiliation:
Dpt. of Pathology; Dpt. of Land Economy; King's College, Cambridge
http://www.landecon.cam.ac.uk/directory/goylette-c...

Research Interests:

-Geographical focus is sub-Saharan Africa; key study sites- Lake Victoria & Lake Albert in Uganda -identification of morbidity attributable to human helminthiasis (worms) -complex network analyses, particularly social networks but also spatial, transmission, and comorbidity networks -RCTs and quasi-experimental analyses -artefactual/behavioural experiments -microeconometrics, health economics, 'big data' approaches

Publications:
Chami G.F., Kontoleon A., Bulte E., Fenwick A., Kabatereine N., Tukahebwa E., Dunne D.W. Profiling nonrecipients of mass drug administration for schistosomiasis and hookworm infections: a comprehensive analysis of praziquantel and albendazole coverage in community-directed treatment in Uganda. Clinical Infectious Diseases. 2016;62:200-207.

Chami G.F., Fenwick A., Bulte E., Kontoleon A., Kabatereine N., Tukahebwa E., Dunne D.W. Influence of S. mansoni and hookworm infection intensities on anaemia in Ugandan villages. PLOS Neglected Tropical Diseases. 2015;9:e0004193.

Chami G.F., Molyneux D.H., Kontoleon A.A., & Dunne D.W. Exploring network theory for mass drug administration. Trends in Parasitology. 2013; 29:370-379

Mr Paul Chinnock (Systematic Reviews) More Info

Position & Affiliation:
Independent editor and writer, specialising in global health and in systematic review; Senior member: Hughes Hall, University of Cambridge. Honorary lecturer: London School of Hygiene & Tropical Medic
http://www.hughes.cam.ac.uk/about-us/the-fellowshi...

Research Interests:

Methodology: systematic review (evidence-based medicine), assessing the quality of research (peer review), publishing, effective science communication.
Topic areas: ‘tropical’ diseases (infectious diseases of poverty), nutrition, non-communicable diseases, injury, ageing (dementia).

Suggestions for specific projects/topics: Research programmes should both begin and end with a systematic review of all the available evidence. I could advise on this and on getting completed research published in peer-reviewed journals.

Existing African or developing country associations: I currently act as rapporteur for conferences and meetings of The European & Developing Countries Clinical Trials Partnership. The partnership involves both African and European nations and is headquartered in The Hague and in Cape Town.

Publications:
(1) Nabarro D, Chinnock P. Growth monitoring: inappropriate promotion of an appropriate technology. Soc Sci Med 1988; 26(9): 941–8.


(2) Chinnock P, Siegfried N, Clarke M. Is evidence-based medicine relevant to the developing world? PLoS Medicine 2005; 2(4): 0100-2.

(3) Ker K, Chinnock P. Interventions in the alcohol server setting for preventing injuries. Cochrane Database Syst Rev. 2008 Jul 16;(3):CD005244.

Dr Tinashe Chiurugwi (Agriculture) More Info

Position & Affiliation:
Research Associate

Research Interests:

• As part of the NIAB International initiative, I am exploring ways (project development and fundraising) to apply NIAB skills and experience to agricultural issues in developing countries.

• I am currently focussed on determining how the NIAB Innovation Farm concept (a knowledge exchange/technology transfer hub) could be applied in Ghana, Uganda, Kenya and Zimbabwe. This work is funded by the John Templeton Foundation through the Biosciences for Farming in Africa project (B4FA.org).

Possible project topic: Collaborations that seek to apply NIAB skills in pre-breeding research, plant variety evaluation, seed certification and knowledge exchange in the Crops Industry.

Current African/developing country associations: Links with various members of National Agricultural Research and Extension Systems, Universities, private companies, and non-profit organisations involved with the Crops Industries of Ghana, Uganda, Kenya and Zimbabwe.

Dr Isabel Clare (Mental Health & Intellectual Disabilities) More Info

Position & Affiliation:
Affiliated Lecturer, Cambridge Intellectual and Developmental Disabilities Research Group, Dept of Psychiatry; Consultant Clinical and Forensic Psychologist
http://www.ciddrg.org.uk/

Research Interests:

Mental health and social care legislation, policy, and practice for people with intellectual or other developmental disabilities. The criminal justice system and suspects/defendants, victims, and witnesses with mental health difficulties.

Possible project topics: For any of the topics listed above, I am able to supervise projects using quantitative or qualitative methodologies, and adopting a psychological, sociological, comparative and/or human rights perspective.

Publications:
(1) Jacob R et al. (2005). Self-harm, capacity and refusal of treatment: Implications for emergency medical practice, Emergency Medicine Journal, 22, 799-802.

(2) Fistein EC et al. (2009). A comparison of mental health legislation from diverse Commonwealth jurisdictions. International Journal of Law and Psychiatry, 32, 147-155.

(3) Murphy GH and Clare ICH (2009). Intellectual disabilities and decision-making, in (Eds.) S.Young, M. Kopelman and G.H. Gudjonsson. Handbook of Forensic Neuropsychology, pp. 53-79.Oxford: Oxford University Press.

Dr Alasdair Coles (Multiple Sclerosis & Demyelinating Diseases In Africa) More Info

Position & Affiliation:
Senior Lecturer in Neuroimmunology, Dept of Clinical Neurosciences
http://www.neuroscience.cam.ac.uk/directory/profil...

Research Interests:

Multiple sclerosis and monoclonal antibody therapy.

Possible project topic: Phenotype of demyelinating illness in Africa. Current African links: I have worked as a neurologist in Nigeria.

Publications:
(1) Jones JL et al. (2009), IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H). J Clin Invest 119(7):2052-61.

(2) CAMMS223 Trial Investigators, Coles AJ et al. (2008), Alemtuzumab vs. Interferon beta-1a in early multiple sclerosis. N Engl J Med 359(17):1786-801.

Dr William Colledge (Neuroendocrine Regulation Of Fertility) More Info

Position & Affiliation:
Professor of Reproductive Physiology, Dept of Physiology, Development and Neuroscience
http://www.pdn.cam.ac.uk/groups/colledgelab/index....

Research Interests:

Neuroendocrine regulation of fertility. Role of kisspeptin signalling in implantation and placental function.

Publications:
(1) d'Anglemont de Tassigny, X. et al. (2008). Kisspeptin can stimulate GnRH release by a direct action at GnRH nerve terminals. Endocrinology 149: 3926-3932.

(2) d'Anglemont de Tassigny, X. et al. (2007) Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci USA. 104: 10714-10719.

(3) Seminara, S.B., et al. (2003). The GPR54 gene as a regulator of puberty. N. Engl. J. Med. 349:1614-1627.

Prof Peter Collins (Molecular Genetics Of Brain Tumours) More Info

Position & Affiliation:
Professor of Histopathology and Morbid Anatomy, Honorary Consultant Histopathologist. Head of Division of Molecular Histopathology, Dept of Pathology
www.path.cam.ac.uk

Research Interests:

Molecular genetics of brain tumours; genomics platform development.

Publications:
(1) Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Jones DT et al. Cancer Res. 2008 Nov 1; 68 (21) : 8673-7. PMID: 18974108.

(2) IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas. Ichimura K et al. Neuro Oncol. 2009 Aug; 11 (4): 341-7. Epub 2009 May 12. PMID: 19435942.

(3) Real-time quantitative polymerase chain reaction (qPCR) analysis with fluorescence resonance energy transfer (FRET) probes reveals differential expression of the four ERBB4 juxtamembrane region variants between medulloblastoma and pilocytic astrocytoma. Zeng N et al. Neuropathol Appl Neurobiol. 2009 Aug; 35 (4): 353-66. Epub 2008 Nov 12. PMID : 19017278.

Dr James Cotton (Population genomics of Neglected Tropical Disease parasites) More Info

Position & Affiliation:
Senior Staff Scientist, Wellcome Trust Sanger Institute
http://www.sanger.ac.uk/people/directory/cotton-ja...

Research Interests:

Comparative and population genomics of parasites, particularly those causing neglected tropical disease. Current projects are on Schistosoma, Leishmania, and Cryptosporidium. I am also interested and involved in using veterinary helminths as models for the genetics and evolution of anthelminthic drug resistance. I work with Matt Berriman as part of the larger parasite genomics group at WTSI.

Publications:
Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent, 2016, eLife. PUBMED: 27003289

Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection. 2016, Scientific Reports. PUBMED: 27003289

The genome of Onchocerca volvulus, agent of river blindness. 2016, Nature Microbiology; doi:10.1038/nmicrobiol.2016.216

Dr Tim J Croudace More Info

Position & Affiliation:

Research Interests:

Dr Heather Cruickshank (Sustainable Development and Engineering) More Info

Position & Affiliation:
University Lecturer, Centre for Sustainable Development, Department of Engineering
http://www-csd.eng.cam.ac.uk/people/staff/cruicksh...

Research Interests:

Sustainable Development
Infrastructure
Capacity Building

Relevant current projects:
EPSRC/DFID/DECC Energy and Low Income Tropical Housing Project: www.elith.eng.cam.ac.uk
Smart Villages Project: www.E4SV.org

Current African links:
Current Research projects in Tanzania and Uganda (and also China and Thailand).
Past projects in Kenya and South Africa (and also Afghanistan, Nepal and elsewhere)

Dr Devon Curtis (Politics and International Relations) More Info

Position & Affiliation:
Lecturer in Politics and International Studies, Department of Politics and International Studies
http://www.polis.cam.ac.uk/Staff_and_Students/dr-d...

Research Interests:

Dr Curtis offers research supervision on a variety of topics in African politics and international relations. She is particularly interested in research projects that focus on peacebuilding, humanitarianism, rebel movements and non-state actors, and the politics of north-south and south-south engagement.